From diagnostics to cannabis-based therapeutics, Sophie Topham’s career in biotech patent law has been anything but predictable. A Senior Associate in the biotechnology team at Marks & Clerk, Sophie’s calm, analytical approach is matched by a refreshing curiosity—qualities that have made her an invaluable asset to clients and colleagues alike. We caught up with her to hear about her work, career path, and the rare case that led to one of her most widely read articles.
From Immunology to Innovation
Sophie’s current docket spans a broad range of biotechnology innovations. While she regularly works with immunology-based diagnostics and oncology-related inventions (including peptide vaccines and tools for identifying oncogenic mutations), her work is as diverse as the biotech field itself.
“Over the last few years, I’ve also worked in the cannabis field, particularly with extracts and synthetic cannabinoids for medical uses,” she explains. “And more recently, I’ve seen an increase in devices—some that resemble ELISAs on a chip, others that use antibodies in more novel ways.”
Despite the increasing overlap between biotech and AI, Sophie admits she still has a soft spot for what she calls “pure biology.” “As a biologist by training, those are the ones I find the most intuitive to work with.”
A Curious Case of Prior Art
In 2024, Sophie penned an article about an unusual and educational experience: having a client’s own clinical trial proposal cited as prior art against their European patent. It was the first time she’d encountered such a scenario—and it proved just as useful for the IP community as it did for her personally.
“Opponents in an EPO opposition cited the client’s trial proposal, which we hadn’t seen before due to a team change on the client’s side,” she recalls. “I had to dig into the case law to understand how such documents are interpreted, especially regarding whether the invention was truly disclosed.”
The case raised interesting questions around whether and how other documents—such as scientific publications—can be used to interpret clinical trial proposals, and how that squares with the EPO’s guidelines.
Understanding the Unusual
Sophie is quick to point out that having clinical trial proposals cited as prior art is still uncommon. “Patent applications in biotech typically don’t require clinical data to be granted. In vitro data is often sufficient for meeting plausibility requirements, so most companies file before trials begin,” she says.
Still, her experience highlighted how easy it is for assumptions to trip up even the most diligent teams. “We’ve seen clients express genuine surprise that their own publications can be cited against them—especially in Europe where there’s no grace period.”
The Route Not Taken
Like many in the IP profession, Sophie’s path wasn’t a straight line. “I originally wanted to be an airline pilot,” she laughs. “But when airlines stopped sponsoring training, the cost became unrealistic. Then I remembered a careers talk we had at university about being a patent attorney. I looked into it, and here I am.”
With a background in biological natural sciences from Cambridge, Sophie’s analytical mindset found a perfect home in IP law. She’s since seen applications through from drafting to grant, oppositions, and even appeals.
“Seeing something I’ve written be granted—and knowing I helped a startup gain recognition through their patent—those are the highlights,” she says.
Life Outside the Office
When she’s not deep in a patent claim, Sophie is rarely still. “I always try to move—walk, cycle, yoga, strength training. Even when working from home, I’ll build exercise into my day.” She’s part of a cycling club and makes time for a proper lunch break most days—usually with some kind of movement.
Evenings are more relaxed: cooking from scratch, reading anything from spy novels to translated Japanese fiction, and planning her next getaway. This summer, she’ll finally fulfil a childhood dream—horse riding along the beaches of Morocco with her twin sister.
If Only There Were More Hours…
When asked which fictional invention she’d most like to patent, Sophie doesn’t hesitate: “Hermione Granger’s Time-Turner. I’d love more hours in the day. If I knew how it worked, I’d make one!”
With her blend of sharp legal insight and grounded, genuine enthusiasm for the science behind the patents, Sophie brings a distinct human touch to biotech IP. Whether she’s tackling tricky prior art or galloping down a Moroccan beach, she’s doing it with purpose and passion.
Marks & Clerk is a leading international firm of intellectual property experts, providing comprehensive patent, trade mark, design, and litigation services. With a global presence and deep sector knowledge, Marks & Clerk supports innovative companies from startups to multinationals in protecting and leveraging their IP assets.
How PatWorld Supports Biotech Innovators
At PatWorld, we help biotech companies, attorneys, and researchers access fast, reliable, and intuitive global patent search tools. Our advanced search and analytics features enable professionals like Sophie to:
Triathlons, Chemistry, and Patents – The Unique Path of Yann Robin, Marks & Clerk
In this edition of our Meet the IP Professional series, PatWorld is delighted to feature Yann Robin, a Principal Associate and Patent Attorney at Marks & Clerk. With a career spanning over 17 years, Yann has built a reputation for his meticulous approach to intellectual property, combining technical expertise with a deep understanding of client needs. We spoke to Yann about his journey through triathlons, chemistry and patents, the evolving role of foreign languages in patent law, and the importance of tailoring IP strategies to meet diverse client priorities.
Falling into IP: Yann’s Unexpected Path
Unlike some who enter the IP profession with a clear vision, Yann’s path was more serendipitous. After completing his postgraduate studies at the University of Strathclyde, Yann began his career at Thomson Derwent, working on patent classification tools. His work involved assigning codes to patents, particularly in the field of chemistry and polymers. This experience sparked his interest in patents and naturally led him to pursue a career as a patent attorney.
“I didn’t have a lifelong ambition to work in IP; I simply followed the opportunities my career presented,” Yann reflects. “But I’m glad I did. It’s a fascinating and rewarding field.”
The Power of Languages in IP Practice
As a native French speaker, Yann’s language skills have long been an asset in his practice. When he started in the profession in 2007, proficiency in a second language—particularly one of the EPO’s official languages—was highly valued. This was because access to machine-generated English translations was not as widespread as it is today.
While machine translation tools have advanced dramatically, Yann highlights that fluency in foreign languages remains invaluable in certain circumstances. “There are still instances where a precise understanding of a foreign language is essential,” he explains. For example, a recent freedom-to-operate analysis required Yann to review a French competitor’s EP patent and the associated French prior art. In this case, subtle linguistic nuances in the claims and prior art documents meant machine translations could not be solely relied upon. Yann’s fluency in French allowed him to provide his client with the clarity needed to make a sound commercial decision.
Although machine translations will likely continue to improve, Yann believes there will always be circumstances where working with the original language is indispensable. The subtleties of technical and legal terms often defy perfect translation, making human expertise a necessity.
Tailoring IP Strategies to Diverse Client Needs
Yann’s client base is diverse, ranging from individual innovators and start-ups to SMEs and multinational corporations. This breadth of experience has reinforced his belief that no two clients are the same. “The most critical point is to first understand the client’s situation and commercial goals, both short-term and long-term,” he says.
He recalls a client, a local SME specialising in cancer diagnostics, who successfully secured a significant round of funding. Their robust patent portfolio, developed with Yann’s guidance over a decade, played a key role in this achievement. This example underscores the importance of aligning IP strategy with a company’s growth trajectory and commercial objectives.
Yann emphasises that budget constraints often shape the IP strategies of start-ups and SMEs. He and his team at Marks & Clerk address this by offering tailored solutions, including a dedicated Start-up Offering and access to IP Audits to help businesses get a cost-effective start on their IP journey.
Sustainable Innovation: A Personal and Professional Interest
Sustainability is a growing area of importance in IP. I find it exciting both technologically and because it aligns with my belief that we need to find solutions to the environmental challenges we face.
Combining his professional expertise with personal values, Yann is actively involved in Marks & Clerk’s Sustainable Materials Group. This initiative focuses on supporting clients developing eco-friendly and innovative materials. “Sustainability is a growing area of importance in IP,” Yann explains. “I find it exciting both technologically and because it aligns with my belief that we need to find solutions to the environmental challenges we face.”
Building Long-Term Relationships
For Yann, building trusted, long-term relationships with clients is fundamental. “Our job is to advise as best we can, and that means understanding the people behind the businesses,” he notes. Regular dialogue and staying attuned to a client’s evolving needs enable him to deliver advice that is not only legally sound but also commercially practical.
Advice for Aspiring IP Professionals
For those considering a career in intellectual property, Yann offers honest and practical advice: “Be patient and stay humble. It takes time to develop the technical, legal, and client-facing skills needed to become truly independent as a patent attorney. You may come into the profession with an impressive academic background, but you’ll need to embrace the learning process, sometimes at a pace which may feel frustratingly slow”
Beyond the Office: Triathlons, Trail Runs, and Outdoor Adventures
Away from the world of patents, Yann is a passionate outdoor enthusiast. He enjoys trail running, cycling, open-water swimming, and competing in triathlons. “I’ve been doing triathlons for almost 10 years now,” Yann shares. “Like most people who dip into that world later in life, I started with shorter distances like Sprint or Olympic, then moved on to longer distances. I tend to do a couple of events a year. I completed my first Ironman distance last summer in Northumberland, finishing an unexpected third overall. One of the most unusual events I did was a half-ironman night race near Aviemore, starting at midnight with a swim in Loch Morlich in complete darkness, followed by biking through the night and running up Cairn Gorm at sunrise—a truly unique experience!”
He also has a lesser-known trait—a photic sneeze reflex. “I sneeze when I look at bright sunlight,” he laughs. “Apparently, it affects around 20% of people, but it still surprises my colleagues!”
Looking to the Future
Yann predicts that while machine translation tools will continue to improve, the need for human linguistic and cultural understanding will persist. The nuances of IP law and the complexity of technical inventions will always require the expertise of a skilled professional who can interpret beyond the limitations of automated tools.
At PatWorld, we understand the importance of precision and insight in IP research and analysis. We are proud to support professionals like Yann Robin with our expert patent search services, helping firms make informed decisions with confidence. Whether you require a freedom-to-operate search, prior art search, or competitor analysis, PatWorld’s experienced team is here to assist. Find out more and order a search at https://patworld.com/gb/order-a-search/.
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